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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1964 2
1965 1
1967 1
1971 1
1972 1
1973 2
1975 7
1976 4
1977 4
1978 6
1979 13
1980 8
1981 8
1982 11
1983 18
1984 6
1985 16
1986 11
1987 18
1988 8
1989 32
1990 19
1991 32
1992 22
1993 36
1994 34
1995 36
1996 35
1997 44
1998 55
1999 47
2000 57
2001 79
2002 74
2003 81
2004 70
2005 103
2006 111
2007 108
2008 151
2009 175
2010 166
2011 151
2012 207
2013 232
2014 223
2015 229
2016 250
2017 281
2018 296
2019 329
2020 364
2021 437
2022 511
2023 503
2024 192

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5,401 results

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Page 1
Lysosomal potassium channels.
Wu Y, Xu M, Wang P, Syeda AKR, Huang P, Dong XP. Wu Y, et al. Cell Calcium. 2022 Mar;102:102536. doi: 10.1016/j.ceca.2022.102536. Epub 2022 Jan 6. Cell Calcium. 2022. PMID: 35016151 Review.
However, our understanding about how lysosomal K(+)homeostasis is regulated and what are the functions of K(+)in the lysosome is very limited. Currently, two lysosomal K(+)channels have been identified: large-conductance Ca(2+)-activated K(+)channel (BK) and transme …
However, our understanding about how lysosomal K(+)homeostasis is regulated and what are the functions of K(+)in the lysosome is very limite …
Research Progress on TRPA1 in Diseases.
Li J, Zhang H, Du Q, Gu J, Wu J, Liu Q, Li Z, Zhang T, Xu J, Xie R. Li J, et al. J Membr Biol. 2023 Dec;256(4-6):301-316. doi: 10.1007/s00232-023-00277-x. Epub 2023 Apr 11. J Membr Biol. 2023. PMID: 37039840 Free PMC article. Review.
For a long time, the physiological activity of TRP ion channels and the response to various stimuli have been the focus of attention, and the physiological functions mediated by ion channels have subtle links with the occurrence of various diseases. Our group has be …
For a long time, the physiological activity of TRP ion channels and the response to various stimuli have been the focus of attention, …
Cardiac ion channels.
Priest BT, McDermott JS. Priest BT, et al. Channels (Austin). 2015;9(6):352-9. doi: 10.1080/19336950.2015.1076597. Epub 2015 Aug 20. Channels (Austin). 2015. PMID: 26556552 Free PMC article. Review.
At the same time, off-target interactions of drugs with cardiac ion channels can be the cause of unwanted side effects. This manuscript aims to review the physiology and pharmacology of key cardiac ion channels. The intent is to highlight recent developments for the …
At the same time, off-target interactions of drugs with cardiac ion channels can be the cause of unwanted side effects. This manuscri …
Cannabidiol and Sodium Channel Pharmacology: General Overview, Mechanism, and Clinical Implications.
Ghovanloo MR, Ruben PC. Ghovanloo MR, et al. Neuroscientist. 2022 Aug;28(4):318-334. doi: 10.1177/10738584211017009. Epub 2021 May 24. Neuroscientist. 2022. PMID: 34027742 Free PMC article. Review.
Treating those mutations that increase the excitability of Nav channels requires inhibitors that could effectively reduce channel firing. The main non-psychotropic constituent of the cannabis plant, cannabidiol (CBD), has recently gained interest as a viable compoun …
Treating those mutations that increase the excitability of Nav channels requires inhibitors that could effectively reduce channel …
The bare necessities of plant K+ channel regulation.
Lefoulon C. Lefoulon C. Plant Physiol. 2021 Dec 4;187(4):2092-2109. doi: 10.1093/plphys/kiab266. Plant Physiol. 2021. PMID: 34618033 Free PMC article. Review.
Plant K+ channels are members of the superfamily of voltage-dependent K+ channels, or Kv channels, that include the Shaker channels first identified in fruit flies (Drosophila melanogaster). Kv channels have been studied in depth over the …
Plant K+ channels are members of the superfamily of voltage-dependent K+ channels, or Kv channels, that include the Sha …
KCNE2 and the K (+) channel: the tail wagging the dog.
Abbott GW. Abbott GW. Channels (Austin). 2012 Jan-Feb;6(1):1-10. doi: 10.4161/chan.19126. Epub 2012 Jan 1. Channels (Austin). 2012. PMID: 22513486 Free PMC article. Review.
KCNE2, originally designated MinK-related peptide 1 (MiRP1), belongs to a five-strong family of potassium channel ancillary (beta) subunits that, despite the diminutive size of the family and its members, has loomed large in the field of ion channel physiology. KCNE …
KCNE2, originally designated MinK-related peptide 1 (MiRP1), belongs to a five-strong family of potassium channel ancillary (beta) su …
Manipulation of ion channel gating with photoswitchable tweezers.
Dunning K, Grutter T. Dunning K, et al. Methods Enzymol. 2021;653:349-376. doi: 10.1016/bs.mie.2020.12.021. Epub 2021 Jan 27. Methods Enzymol. 2021. PMID: 34099179
The modulation of ion channel activity is of central importance within the nervous system, and an in-depth understanding of how such activity occurs on the molecular level is of prime importance for enhancing our understanding of neuronal systems in physiological an …
The modulation of ion channel activity is of central importance within the nervous system, and an in-depth understanding of ho …
The effect of increased channel interaction on speech perception with cochlear implants.
Goehring T, Archer-Boyd AW, Arenberg JG, Carlyon RP. Goehring T, et al. Sci Rep. 2021 May 17;11(1):10383. doi: 10.1038/s41598-021-89932-8. Sci Rep. 2021. PMID: 34001987 Free PMC article.
Instead of using a single electrode per channel as in standard CI processing, spectral blurring used up to 6 electrodes per channel simultaneously to increase the overlap between adjacent frequency channels as would occur in cases with severe channel i …
Instead of using a single electrode per channel as in standard CI processing, spectral blurring used up to 6 electrodes per channe …
Transient Receptor Potential Canonical 7 (TRPC7), a Calcium (Ca(2+)) Permeable Non-selective Cation Channel.
Zhang X, Spinelli AM, Masiello T, Trebak M. Zhang X, et al. Adv Exp Med Biol. 2016;898:251-64. doi: 10.1007/978-3-319-26974-0_11. Adv Exp Med Biol. 2016. PMID: 27161232 Review.
Transient receptor potential canonical subfamily, member 7 (TRPC7) is the most recently identified member of the TRPC family of Ca(2+)-permeable non-selective cation channels. The gene encoding the TRPC7 channel plasma membrane protein was first cloned from mouse br …
Transient receptor potential canonical subfamily, member 7 (TRPC7) is the most recently identified member of the TRPC family of Ca(2+)-perme …
Meddling with Fate: The Proteasomal Deubiquitinating Enzymes.
de Poot SAH, Tian G, Finley D. de Poot SAH, et al. J Mol Biol. 2017 Nov 10;429(22):3525-3545. doi: 10.1016/j.jmb.2017.09.015. Epub 2017 Oct 5. J Mol Biol. 2017. PMID: 28988953 Free PMC article. Review.
As translocation proceeds, ubiquitin chains bound to substrate are drawn to the channel's entry port, where they can impede further translocation. ...A major challenge for the field will be to elucidate the specificities of Rpn11, Usp14, and Uch37 in greater dept …
As translocation proceeds, ubiquitin chains bound to substrate are drawn to the channel's entry port, where they can impede fu …
5,401 results